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“Background. Knowledge of the basic processes determinative of the life courses of older persons has progressed dramatically in the past few years. This article is an update of a similar survey performed 27 years ago.
Methods. A literature review of recent contributions gathered front a variety of disciplines seeks a more
sturdy and consistent heuristic from which derivative work may proceed.
Results. Publications from basic and clinical sciences as well as related nonmedical fields reveal a new conceptual framework for the understanding of human aging, which suggests a broader framework of contributing agencies and their policy implications.
Conclusions. Aging is not a disease and therefore demands a different lens
for analysis. This selleck screening library article provides a deeper focus and insists on the inclusion of a heightened sense of the participation of time. Incorporation of the imperatives applied by the Second Law of Thermodynamics is the foundation of the new definitions.”
“BACKGROUND: The accurate position of the ventricular catheter inside the frontal horn of the lateral ventricle is essential to prevent proximal failure in shunt surgery. For optimal placement, endoscopic- and image-guided techniques are available.
OBJECTIVE: We introduce a newly constructed tool for quick and safe placement of ventricular catheters. It is mounted on a fixation device selleckchem and therefore allows the surgeon’s optimal concentration on the catheter insertion and feeling for the penetrated tissue. To check the feasibility of the new device, we performed a study with 4 patients.
METHODS: Two patients with communicative and 2 patients with noncommunicative hydrocephalus underwent ventricular catheter placement using the new shunt placement tool. Three patients had a
complex anatomy of the ventricular system.
RESULTS: In all 4 procedures, correct placement of the ventricular catheters was achieved. The additional time needed for preparations did not exceed 15 minutes. The comparison of the postoperative computed tomography scans with the preoperative planning showed good accuracy of the instrument with a mean deviation of the catheter tips PTK6 from the planned position of 1.5 mm (range 1.0-2.1 mm).
CONCLUSION:The new tool allows safe and quick placement of ventricular catheters. The adjustment of the tool to the planned trajectory is performed before catheter insertion and allows optimal concentration on the insertion procedure and the fingertip feeling for the penetrated tissue.”
“Background. Intra-individual gait variability predicts falls and disability in older people. Knowledge of factors that contribute to gait variability may lead to interventions aimed at reducing decline in mobility and falls risk. The aim of this population-based study was to examine whether poorer performance on a range of sensorimotor measures was associated with greater gait variability.
Methods.