Pearson JP, Pesci EC, Iglewski BH: Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes. J Bacteriol 1997,179(18):5756–5767. 1794649294432CrossRefPubMedCentralPubMed 8. Ochsner UA,

Fiechter A, Reiser J: Isolation, characterization, and expression MK5108 in Escherichia coli of the Pseudomonas aeruginosa rhlAB genes encoding a rhamnosyltransferase involved in rhamnolipid biosurfactant synthesis. J Biol Chem 1994,269(31):19787–19795. 8051059CrossRefPubMed 9. Ochsner UA, Koch AK, Fiechter A, Reiser J: Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa . J Bacteriol 1994,176(7):2044–2054. 2053108144472CrossRefPubMedCentralPubMed 10. Ochsner UA, Reiser J: Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa . Proc Natl Acad Sci U S A 1995,92(14):6424–6428. 10.1073/pnas.92.14.6424415307604006CrossRefPubMedCentralPubMed 11. Fuqua C, Greenberg EP: Self perception in bacteria: quorum sensing with acylated homoserine lactones. Curr Opin Microbiol 1998,1(2):183–189. 10.1016/see more S1369-5274(98)80009-X10066485CrossRefPubMed

12. Medina G, Juarez K, Soberon-Chavez G: The Pseudomonas aeruginosa rhlAB operon is not expressed during the logarithmic phase of growth even in the presence of its activator RhlR and the autoinducer N-butyryl-homoserine lactone. J Bacteriol 2003,185(1):377–380. 10.1128/JB.185.1.377-380.200314183612486077CrossRefPubMedCentralPubMed 13. Pesci EC, Pearson JP, Seed PC, Iglewski BH: Regulation BTSA1 molecular weight of las and rhl quorum sensing in Pseudomonas aeruginosa . J Bacteriol 1997,179(10):3127–3132. 1790889150205CrossRefPubMedCentralPubMed 14. Dekimpe V, Deziel E: Revisiting the quorum-sensing hierarchy in Pseudomonas aeruginosa : the transcriptional regulator RhlR regulates LasR-specific factors. Microbiology 2009,155(Pt 3):712–723. 19246742CrossRefPubMed 15. Rahim R, Ochsner UA, Olvera C, Graninger M, Messner P, Lam JS, Soberon-Chavez G: Cloning Protein kinase N1 and functional characterization of the Pseudomonas aeruginosa rhlC gene that encodes rhamnosyltransferase 2, an enzyme responsible

for di-rhamnolipid biosynthesis. Mol Microbiol 2001,40(3):708–718. 10.1046/j.1365-2958.2001.02420.x11359576CrossRefPubMed 16. Aguirre-Ramirez M, Medina G, Gonzalez-Valdez A, Grosso-Becerra V, Soberon-Chavez G: The Pseudomonas aeruginosa rmlBDAC operon, encoding dTDP-L-rhamnose biosynthetic enzymes, is regulated by the quorum-sensing transcriptional regulator RhlR and the alternative sigma factor sigmaS. Microbiology 2012,158(Pt 4):908–916. 22262098CrossRef 17. Bazire A, Dheilly A, Diab F, Morin D, Jebbar M, Haras D, Dufour A: Osmotic stress and phosphate limitation alter production of cell-to-cell signal molecules and rhamnolipid biosurfactant by Pseudomonas aeruginosa . FEMS Microbiol Lett 2005,253(1):125–131. 10.1016/j.femsle.2005.09.02916239086CrossRefPubMed 18.