Methods: Patients who failed in their first colonoscopy due to poor bowel preparation were randomly allocated to two groups: next day repeated colonoscopy with sodium phosphate (NaP) 45 mL group (Next day group) vs after 7 days repeated colonoscopy with polyethylene glycol (PEG) 4 L (After 7 days
group). Age, sex, past medical history, current medication, bowel habit, reason for colonoscopy were compared between the two groups. The quality of bowel preparation was assessed using Ottawa scale. Bowel preparation scale, colonoscopic findings and polyp detection Akt inhibitor rate were compared between the two groups. Results: A total of 101 patients with unacceptable colonic preparation were enrolled. Fifty one patients were included in Next day group and fifty patients in After 7 days group. NVP-BGJ398 Next day group showed the better quality of bowel preparation than After 7 days group (4.75 ± 2.45 vs 5.52 ± 2.24, P = 0.003). There was no significant difference in age, sex, current medication, reason for colonoscopy, colonoscopic findings and polyp detection rate between the two groups. Constipation and past history of abdominal surgery was found to be predictive of a failed repeated preparation (Odd ratio = 1.54, 95% CI (1.14–2.07), P = 0.004). Conclusion: Second colonoscopy
on next day with NaP 45 mL was more effective than after 7 days with PEG 4 L in colonic preparation failure. Constipation and past history of abdominal 上海皓元 surgery were significant risk factors of repeated preparation failure. Key Word(s): 1. Second colonoscopy; 2. preparation failure; 3. interval Presenting Author: JONG SUN KIM Additional Authors: YOUNG EUN JOO, HYUN SOO KIM, SUNG BUM CHO, WAN SIK LEE Corresponding Author: JONG SUN KIM Affiliations: Chonnam National University Medical School, Chonnam National University Medical School, Chonnam National University Medical School, Chonnam National University Medical School Objective: Adequate bowel preparation is essential for a thorough and accurate examination of the bowel during colonoscopy. Because psychological and environmental stress induces changes in gastrointestinal
motility influencing on bowel preparation, stress could affect degree of bowel cleansing. The goal of this study was to demonstrate the influence of stress on bowel preparation. Methods: A prospective, endoscopist single blind study was conducted. Bowel-cleansing was measured by endoscopists using the Boston bowel preparation scale (BBPS) score. Because all study procedures were conducted between 12 AM and 3 PM, a 4-liter same-day regimen of polyethyleneglycol preparation method is used. We evaluated degree of stress using a global assessment of recent stress (GARS) scale. Results: Five hundred thirty one patients undergoing colonoscopy were enrolled. In multivariate analysis, the GARS scale was significant contributors to satisfactory bowel preparation (p < 0.001).