In terms of surfaces, the labial surface of the molars and incisors was the most frequently affected. The occlusal surface was the least affected but presented the most severe lesions in terms of treatment needing, as in other studies[6, 30, 31]. The reason is probably its morphology, the ease with which it accumulates traces of plaque and is therefore more likely to trigger caries, and its greater involvement in mastication compared with other tooth surfaces. Authors have classed the defect according to its extent and the degree to which it affects the teeth[5, 15, 27,
30], but there is no consensus on classifying the severity of the lesion. MS-275 price Consequently, to find out the social impact of MIH, the present study estimated the treatment need for each molar and incisor of each child with MIH in accordance with the WHO criteria, classified into checkups, non-urgent need and immediate need of care. This resulted in 3.8% of children with MIH needing urgent treatment, which implies severe
involvement and 27.9% needing some kind of treatment other than urgent which could be interpreted as moderately affected, which is similar to the figures reported by Ghanim et al., Lygidakis et al., Kusku et al. One possible bias in PI3K inhibitor this study concerns teeth with atypical restorations mafosfamide with sound margins, with post-eruptive loss of enamel, or with opacities without retentive surface areas or caries, which have been considered at the time of study as needing checkups or preventive treatment where other authors, considering the severity of the lesion, would have classed them as moderate. However, in epidemiological studies, it is usual to estimate severity on the basis of treatment need, and this would allow greater agreement among researchers. Some studies have classed the severity
of MIH according to the number of teeth affected[6, 13, 20, 25, 37]. In the present study, in agreement with these authors, the number of teeth affected increased significantly as the need of treatment rose in terms of urgency. It was also observed, in agreement with Jasulaityte et al. and Chawla et al., that the children with both molars and incisors affected (the MIH group) presented more affected molars and more serious defects which demands treatment than those that only had hypomineralized molars (the MH group). Because of the greater porosity of the tooth structure and, consequently, its lower mechanical resistance, MIH is considered a risk factor for dental caries in low caries prevalence populations[1, 6, 20, 41].