In 2012, incorporation of the GelPoint access platform has the potential to further improve the oncologic performance of VIP, especially in high-risk patients.”
“Objective: In this study, the localization of the headache, mucosal contact points, sinonasal anatomic variations and the incidence of mucosal abnormalities were determined in patients with rhinogenic headache, and the efficacy of the corrective surgery on the severity of the headache and the rate of improvement on that localization were investigated.
Study Design: Conducted in a prospective manner.
Level of Evidence:
Level 2b.
Methods: Sixty-five patients who were admitted with sinonasal SN-38 order symptoms and headache and had septoplasty, endoscopic sinus surgery, or surgical procedures involving the nasal turbinates were included in this study. The quality and the severity of the headache were investigated preoperatively as well as in the 3rd and 12th postoperative months.
Results: Headache was most frequently localized the frontal region. The mucosal contact points were most frequently localized between the nasal septum and the middle or inferior turbinates. Differences between preoperative headache and headache in postoperative 3rd month and postoperative 12th month were statistically significant (P < 0.05). Improvement
in headache after surgery was statistically significant in cases with Haller cell and paradoxical middle turbinate and in patients with contact points between the nasal septum and the middle or inferior turbinates (P < 0.05).
Conclusions: We have
shown the importance of surgery in the treatment of rhinogenic headache. We have see more also shown the reliability of the decongestion test for determining the indication for surgery. We suggest that the rhinologic surgery may have a great contribution to the treatment of headache.”
“The afferent and efferent synaptic connections of the cerebellar nuclei (CN) place them in a key position where they can integrate sensory Ro-3306 signals with the output from cerebellar cortex and to provide the main efferent pathway of the cerebellum. While this conclusion can be derived based on purely anatomical knowledge, it remains unknown in which manner the CN contributes to the generation of cerebellar output signals that are involved in creating timing signals and temporal patters. As a first step towards understanding the role neuronal circuits of the CN, the major CN neuronal types are now identified based on expression patterns of neurotransmitters (GABA and glycine) and characterized both in electrophysiological and morphological manner. The classification-likely to be refined in the future-consists of six types: four classes of projection and two classes of local neurons. The classification is a combination of electrophysiological and morphological methods with the expression pattern of GAD67 and GlyT2, markers for GABAergic and glycinergic neurons, respectively (Uusisaari et al.