“
“Face processing deficits are characteristic of autism spectrum conditions. However, event-related potential studies of autism spectrum conditions have found inconsistent results for the face selective N170 component. In this study, 15 adult males with autism spectrum conditions and 15 matched, typically developing
controls completed a task in which pictures of faces were either attended to or ignored. In the control group, the N170 was larger when faces were attended to. However, there was no such modulation in the autism spectrum conditions group. This finding helps clarify the results from the earlier event-related potential studies of face processing in autism spectrum conditions and suggests that visual attention does not enhance face processing in autism find more spectrum conditions as it does in typical development. NeuroReport 21: 399-403 (C) 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins.”
“Aim:
In the present study, we have cloned a new family of anti-lipopolysaccharide factor (ALF) from haemocytes selleck of kuruma shrimp Marsupenaeus
japonicus (MjALF2) using RACE method.
Methods and Results:
Transcriptional analysis of MjALF2 gene in the organs of healthy shrimp revealed prominent expression in gills and muscle. In vitro LPS stimulation in the lymphoid organ cells resulted in significant increase in expression at 48, 8 and 12 h poststimulation, compared to the nonstimulated cells. In vivo injection of V. penaeicida does not show any high expression in time course assay. Phylogenetic analysis showed MjALF2 is placed in the group closer to
P. monodon isoform 1 and 2 than to MjALF1. The full-length MjALF2 C188-9 ic50 gene consists of 558 bp with a 363 -bp open reading frame, encoding 121 amino acids. The deduced peptide contains a putative signal peptide of 22 amino acids with molecular mass of about 13 center dot 8 kDa molecular mass. The deduced amino acid sequence of MjALF2 showed 83 center dot 3 and 56 center dot 7% identity with ALF sequences of P. monodon.
Conclusions:
The present work revealed the presence of MjALF2 gene, which is highly expressed in gills and muscle of healthy kuruma shrimp. Further studies are required to clarify the involvement of MjALF2 in immune responses for using as a therapeutic agent.
Significance and Impact of the Study:
Antimicrobial peptides are promising potential therapeutic agents for disease control in aquaculture. Understanding the relation of MjALF2 with innate immunity mechanism will lead to develop better health management strategies for long-term sustainability of the shrimp industry.”
“Male Bengalese finches sing complex song sequences during courtship. To examine the female perception of sequence complexity, we tested female auditory processing with respect to sequential differences in the caudomedial nidopallium and caudomedial mesopallium.