Carcinogenesis 2005, 26:1182–1195 PubMedCrossRef

Carcinogenesis 2005, 26:1182–1195.PubMedCrossRef Selleck Go6983 9. Nakanishi

K, Sakamoto M, Yasuda J, Takamura M, Fujita N, Tsuruo T, Todo S, Hirohashi S: Critical involvement of the phosphatidylinositol 3-kinase/Akt pathway in anchorage-independent growth and hematogeneous intrahepatic metastasis of liver cancer. Cancer Res 2002, 62:2971–2975.PubMed 10. Tsurutani J, Steinberg SM, Ballas M, Robertson M, LoPiccolo J, Soda H, Kohno S, Egilsson V, Dennis PA: Prognostic significance of clinical factors and Akt https://www.selleckchem.com/products/ABT-737.html activation in patients with bronchioloalveolar carcinoma. Lung Cancer 2007, 55:115–121.PubMedCrossRef 11. Tang JM, He QY, Guo RX, Chang XJ: Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis.

Lung Cancer 2006, 51:181–191.PubMedCrossRef 12. Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM: Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. eFT-508 Nature 1999, 399:601–605.PubMedCrossRef 13. Coffer PJ, Jin J, Woodgett JR: Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J 1998,335(Pt 1):1–13.PubMed 14. Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E, Frisch S, Reed JC: Regulation of cell death protease caspase-9 by phosphorylation. Science 1998, 282:1318–1321.PubMedCrossRef 15. Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME: Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999, 96:857–868.PubMedCrossRef 16. Kane LP, Shapiro

VS, Stokoe D, Weiss A: Induction of NF-kappaB by the Akt/PKB kinase. Curr Biol 1999, 9:601–604.PubMedCrossRef 17. Muise-Helmericks RC, Grimes HL, Bellacosa A, Malstrom SE, Tsichlis PN, Rosen N: Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol Arachidonate 15-lipoxygenase 3-kinase/Akt-dependent pathway. J Biol Chem 1998, 273:29864–29872.PubMedCrossRef 18. Miao LJ, Wang J, Li SS, Wu YM, Wu YJ, Wang XC: Correlation of P27 expression and localization to phosphorylated AKT in non-small cell lung cancer. Ai Zheng 2006, 25:1216–1220.PubMed 19. Chen Q, Ganapathy S, Singh KP, Shankar S, Srivastava RK: Resveratrol induces growth arrest and apoptosis through activation of FOXO transcription factors in prostate cancer cells. PLoS One 2010, 5:e15288.PubMedCrossRef 20. Nana-Sinkam SP, Geraci MW: MicroRNA in lung cancer. J Thorac Oncol 2006, 1:929–931.PubMedCrossRef 21. Yanaihara N, Caplen N, Bowman E, Seike M, Kumamoto K, Yi M, Stephens RM, Okamoto A, Yokota J, Tanaka T, Calin GA, Liu CG, Croce CM, Harris CC: Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006, 9:189–198.PubMedCrossRef 22. Kumar MS, Erkeland SJ, Pester RE, Chen CY, Ebert MS, Sharp PA, Jacks T: Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci USA 2008, 105:3903–3908.

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