05). The https://www.selleckchem.com/products/poziotinib-hm781-36b.html decrease of the volume of the lower leg was not associated with the decrease in skeletal muscle mass (p >0.05). The change in the lower leg volume was not related to the change in calf circumference (p >0.05). The decrease in estimated skeletal muscle mass was associated with the decrease in body mass (p <0.05) (Figure 1). Table 3 presents the changes in the laboratory results. Haemoglobin, haematocrit, serum [Na+] and serum [K+] remained unchanged (p >0.05). Plasma volume decreased by 0.4 ± 8.8% (p <0.05). Serum
creatinine, serum urea and serum osmolality increased AZD3965 (p <0.05). Urine specific gravity and urine osmolality increased (p <0.05). FENa, FEUrea and creatinine clearance decreased (p <0.05). The potassium-to-sodium ratio in urine and TTPG increased (p <0.05). Table 2 Results of the physical parameters before and after the race ( n = 15). Results are presented as mean ± SD. * = p <0.05 Pre-race Post-race Absolute change Percent change Body mass (kg) 71.3 ± 9.3 68.9 ± 8.8 - 2.4 ± 1.1 * - 3.2 ± 1.3 * Circumference of upper arm (cm) 29.8 ± 2.7 29.3 ± 1.8 - 0.5 ± 1.1 - 1.2 ± 3.7 Circumference of thigh (cm) 54.5 ± 4.4 53.0 ± 4.0 - 1.5 ± 2.1 * - 2.7 ± 3.5 * Circumference of calf (cm) 37.5 ± 2.2 36.5 ± 1.9 - 1.0 ± 1.3 * - 2.4 ± 3.6 * Skin-fold pectoral (mm) 5.8 ± 3.3 5.8 ± 3.1 - 0.0 ± 1.7 - 10.0 ± 45.5 Skin-fold axillar (mm) 8.0 ± 3.3 7.6 ± 3.2 - 0.4 ± 1.0
– 4.8 ± 14.2 Skin-fold triceps (mm) 6.2 ± 2.7 7.0 ± 2.8 BVD-523 + 0.5 ± 1.6 + 11.7 ± 29.1 Skin-fold subscapular (mm) 9.3 ± 3.8 9.2 ± 3.2 – 0.1 ± 1.0 – 1.6 ± 10.7 Skin-fold abdominal (mm) 10.2 ± 5.3 11.1 ± 6.0 + 0.9 ± 1.6 + 8.5 ± 12.9 Skin-fold suprailiacal (mm) 12.6 ± 7.0 12.3 ± 6.6 – 0.3 ± 3.6 – 1.4 ± 22.9 Skin-fold thigh (mm) 9.4 ± 6.3 9.7 ± 6.6 + 0.3 ± 1.8 + 1.6 ± 17.0 Skin-fold calf (mm) 4.6 ± 2.9 4.1 ± 1.8 – 0.5 ± 1.5 – 0.7 ± 23.9 Sum of eight skin-folds (mm) 66.3 ± 30.1 66.8 ± 29.5
+ 0.5 ± 5.0 + 1.5 ± 8.0 Estimated fat mass (kg) 5.6 ± 4.4 5.7 ± 4.7 + 0.1 ± 0.9 + 2.4 ± 15.0 Estimated skeletal muscle mass (kg) 38.9 ± 3.5 37.7 ± 2.6 – 1.2 ± 1.2 * – 2.9 ± 3.0 * Volume of the lower leg (L) 3.85 ± 0.50 3.61 ± 0.44 Phosphoprotein phosphatase – 0.24 ± 0.25 * – 5.86 ± 6.86 * Volume of the arm (L) 2.33 ± 0.44 2.41 ± 0.45 + 0.08 ± 0.49 + 6.15 ± 26.06 Thickness subcutaneous fat at zygomatic arch (mm) 3.56 ± 1.97 2.92 ± 1.14 – 0.64 ± 1.18 – 9.1 ± 30.7 Thickness subcutaneous fat at third metacarpal (mm) 2.92 ± 1.54 2.20 ± 0.86 – 0.72 ± 1.99 – 3.5 ± 78.0 Thickness subcutaneous fat at medial border of the tibia (mm) 2.82 ± 0.73 3.39 ± 1.04 + 0.56 ± 0.82 * + 22.1 ± 29.5 * Thickness subcutaneous fat at medial malleolus (mm) 3.06 ± 1.15 3.58 ± 1.32 + 0.52 ± 1.49 + 28.1 ± 54.5 Thickness subcutaneous fat at medial cuneiform (mm) 2.04 ± 1.08 2.29 ± 1.08 + 0.25 ± 1.57 + 37.2 ± 92.7 Figure 1 The change in skeletal muscle mass was significantly and positively related to the change in body mass ( n = 15) ( r = 0.63, p = 0.012).